LIPC (NM_000236) Human Recombinant Protein
$2,508.00
5 Days*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 53.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000227 |
| Locus ID | 3990 |
| UniProt ID | P11150 |
| Cytogenetics | 15q21.3 |
| RefSeq Size | 1603 |
| RefSeq ORF | 1497 |
| Synonyms | HDLCQ12; HL; HTGL; LIPH |
| Summary | LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. provided by RefSeq, Jul 2008 |
| Protein Categories | Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Glycerolipid metabolism, Metabolic pathways |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Mechanism for the selective uptake of macular carotenoids mediated by the HDL cholesterol receptor SR-BI
Li, George, Vachali et al
Exp Eye Res (2023) 229, 109429 DOI: 10.1016/j.exer.2023.109429
Li, George, Vachali et al
Exp Eye Res (2023) 229, 109429 DOI: 10.1016/j.exer.2023.109429
Cited by 20
AI Summary: OriGene’s recombinant human hepatic lipase (LIPC, #TP315870) was used in this study to investigate its role, alongside SR-BI, in the selective uptake of macular carotenoids by retinal cells.
Snippet: The macular carotenoids lutein and zeaxanthin are taken up from the bloodstream into the human retina through a selective process, for which the HDL cholesterol Save;LEE Biosolutions (Maryland Heights, MO, USA). Recombinant human hepatic lipase (LIPC) was from OriGene Technologies, Inc. (#TP315870;Rockville, MD, USA). SR-BI antibody was from LifeSpan BioSciences, Inc. …
Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway
Ma, Paik, Barile
Invest. Ophthalmol. Vis. Sci. (2014)
Ma, Paik, Barile
Invest. Ophthalmol. Vis. Sci. (2014)
Cited by 8
AI Summary: In this study, OriGene’s recombinant human hepatic lipase (product: TP315870) was used to degrade lipoproteins, enabling the researchers to investigate how the resulting lysophospholipids contribute to complement activation via the classical pathway.
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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