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MTH1 (NUDT1) (NM_198950) Human Recombinant Protein

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SKU
TP312761
Purified recombinant protein of Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 3A, 20 µg
Size:
20 ug 1 mg 100 ug
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC212761 representing NM_198950
Red=Cloning site Green=Tags(s)

MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQI
VFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQ
GQDTILDYTLREVDTV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 17.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_945188
Locus ID 4521
UniProt ID P36639
Cytogenetics 7p22.3
RefSeq Size 740
RefSeq ORF 468
Synonyms MTH1
Summary Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A rare single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. provided by RefSeq, Dec 2018
Protein Categories Intracellular Proteins
Protein Families Stem cell - Pluripotency
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Other "MTH1" proteins (23)
SKU Description Size Price
PH301148 NUDT1 MS Standard C13 and N15-labeled recombinant protein (NP_945190) 10 ug
$3,360.00
PH308551 NUDT1 MS Standard C13 and N15-labeled recombinant protein (NP_002443) 10 ug
$3,360.00
PH312655 NUDT1 MS Standard C13 and N15-labeled recombinant protein (NP_945186) 10 ug
$3,360.00
PH312705 NUDT1 MS Standard C13 and N15-labeled recombinant protein (NP_945187) 10 ug
$3,360.00
PH312761 NUDT1 MS Standard C13 and N15-labeled recombinant protein (NP_945188) 10 ug
$3,360.00
PH312808 NUDT1 MS Standard C13 and N15-labeled recombinant protein (NP_945191) 10 ug
$3,360.00
LC404632 Lyophilized NUDT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC404633 Lyophilized NUDT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC404634 Lyophilized NUDT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC404636 Lyophilized NUDT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC404637 Lyophilized NUDT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419314 Lyophilized NUDT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY404632 Transient overexpression lysate of nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 2A (as WB positive control) 100 ug
$436.00
LY404633 Transient overexpression lysate of nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 2B (as WB positive control) 100 ug
$436.00
LY404634 Transient overexpression lysate of nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 3A (as WB positive control) 100 ug
$436.00
LY404636 Transient overexpression lysate of nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 4A (as WB positive control) 100 ug
$436.00
LY404637 Transient overexpression lysate of nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 4B (as WB positive control) 100 ug
$436.00
LY419314 Transient overexpression lysate of nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP301148 Recombinant protein of human nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 3B, 20 µg 20 ug
$867.00
TP308551 Purified recombinant protein of Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 1, 20 µg 20 ug
$867.00
TP312655 Recombinant protein of human nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 2A, 20 µg 20 ug
$867.00
TP312705 Recombinant protein of human nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 2B, 20 µg 20 ug
$867.00
TP312808 Purified recombinant protein of Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 1 (NUDT1), transcript variant 4A, 20 µg 20 ug
$867.00

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