PF4 (NM_002619) Human Recombinant Protein
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 10.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Cell treatment (PMID: 28120850) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002610 |
| Locus ID | 5196 |
| UniProt ID | P02776 |
| Cytogenetics | 4q13.3 |
| RefSeq Size | 878 |
| RefSeq ORF | 303 |
| Synonyms | CXCL4; PF-4; SCYB4 |
| Summary | This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. provided by RefSeq, Oct 2014 |
| Protein Categories | Chemokines, Cytokines, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PF4" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH311322 | PF4 MS Standard C13 and N15-labeled recombinant protein (NP_002610) | 10 ug |
$3,360.00
|
|
| LC400930 | Lyophilized PF4 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400930 | Transient overexpression lysate of platelet factor 4 (PF4) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection
Guo, Feng, Wang et al
Mucosal Immunol (2017)
Guo, Feng, Wang et al
Mucosal Immunol (2017)
AI Summary: OriGene’s recombinant CXCL4 protein was used to treat CXCL4-deficient mice, enabling the researchers to specifically assess the role of CXCL4 in influenza-induced lung pathology.
Snippet: To demonstrate CXCL4-specific effects in the CXCL4 −/− mice, H1N1-infected CXCL4 −/− mice were given recombinant CXCL4 (5 μg per mouse) (OriGene, Beijing, China) on day 0 and daily postinfection by intravenous injection via the retro-orbital plexus as described ... Cite SaveSaving
Showing 1-1 of 1 papers.
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