Gemin 2 (GEMIN2) (NM_003616) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 31.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003607 |
| Locus ID | 8487 |
| UniProt ID | O14893 |
| Cytogenetics | 14q21.1 |
| RefSeq Size | 1368 |
| RefSeq ORF | 840 |
| Synonyms | SIP1; SIP1-delta |
| Summary | This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. provided by RefSeq, Aug 2011 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Gemin 2" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH311219 | SIP1 MS Standard C13 and N15-labeled recombinant protein (NP_003607) | 10 ug |
$3,360.00
|
|
| LC418547 | Lyophilized GEMIN2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422905 | Lyophilized GEMIN2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418547 | Transient overexpression lysate of survival of motor neuron protein interacting protein 1 (SIP1), transcript variant alpha (as WB positive control) | 100 ug |
$436.00
|
|
| LY422905 | Transient overexpression lysate of survival of motor neuron protein interacting protein 1 (SIP1), transcript variant gamma (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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