GRP94 (HSP90B1) (NM_003299) Human Recombinant Protein

  • Product Brand Image
SKU
TP309563
Recombinant protein of human heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1), 20 µg
  $737.00
In Stock*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC209563 protein sequence
Red=Cloning site Green=Tags(s)

MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELR
EKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDK
EKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVI
VTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIY
VWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEV
EEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITD
DFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGT
NIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLK
KGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDK
IEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRR
IKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDT
TEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 90.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003290
Locus ID 7184
UniProt ID P14625
Cytogenetics 12q23.3
RefSeq Size 2879
RefSeq ORF 2409
Synonyms ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
Summary This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. provided by RefSeq, Aug 2012
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "GRP94" proteins (3)
SKU Description Size Price
PH309563 HSP90B1 MS Standard C13 and N15-labeled recombinant protein (NP_003290) 10 ug
$3,360.00
LC418780 Lyophilized HSP90B1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418780 Transient overexpression lysate of heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1) (as WB positive control) 100 ug
$436.00

file-alt Citations

Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response
Gómez-Fernández, Urtasun, Paton et al
Front Immunol (2018) 9, 2934 DOI: 10.3389/fimmu.2018.02934
AI Summary: OriGene contributed IL22RA2v2 myc-FLAG tag plasmid (RC219095) and vectors expressing C-terminal Myc-FLAG-tagged IL22RA2v2, IL-2, IL-4, IL-10, IL-17, IL-22, IFN-γ, and GRP94, which were used to study the secretion, function, and chaperone interactions of IL-22BP isoforms in this research.
Snippet: IL22RA2v2 myc-FLAG tag and IL22RA2v3-FLAG tag plasmids were, respectively purchased from Origene (RC219095) and GenScript (Ohu00490). …Vectors expressing C-terminal Myc-FLAG-tagged IL22RA2v2, IL-2, IL-4, IL-10, IL-17, IL-22, IFN-γ, and GRP94 were from Origene
FigureFigureFigure
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products