Radixin (RDX) (NM_002906) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 68.4 kDa |
| Concentration | >200 ug/mL as determined by Microplate Bradford Protein Assay method |
| Purity | > 95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002897 |
| Locus ID | 5962 |
| UniProt ID | P35241 |
| Cytogenetics | 11q22.3 |
| RefSeq Size | 4498 |
| RefSeq ORF | 1749 |
| Synonyms | DFNB24 |
| Summary | Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2012 |
| Protein Categories | Growth Factors, Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Regulation of actin cytoskeleton |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Radixin" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH307953 | RDX MS Standard C13 and N15-labeled recombinant protein (NP_002897) | 10 ug |
$3,360.00
|
|
| LC401020 | Lyophilized RDX HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401020 | Transient overexpression lysate of radixin (RDX) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?
Miyaji, Shahrizaila, Umapathi et al
Hum. Immunol. (2014)
Miyaji, Shahrizaila, Umapathi et al
Hum. Immunol. (2014)
Cited by 12
AI Summary: OriGene’s purified recombinant human ezrin, radixin, and moesin proteins were used as antigens in ELISA assays to test for autoantibodies in patient samples, helping determine that these ERM proteins are unlikely targets in demyelinating neuropathies.
Snippet: each hospital local ethics approval. 2.2. ELISA. Purified recombinant ERM proteins of Homo sapiens, produced in HEK293 cells, were purchased from OriGene Technologies, Inc. (Rockville, MD, USA). The wells of microplates ... Cite SaveSaving
Showing 1-1 of 1 papers.
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