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PTGR1 (NM_012212) Human Recombinant Protein

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SKU
TP306692
Recombinant protein of human prostaglandin reductase 1 (PTGR1), 20 µg
Size:
20 ug 1 mg 100 ug
  $867.00
In Stock*
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Frequently Bought Together (2)

TA315207 Rabbit polyclonal anti-PTGR1 antibody
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC206692 protein sequence
Red=Cloning site Green=Tags(s)

MVRTKTWTLKKHFVGYPTNSDFELKTSELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAK
VVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVK
GGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDG
YDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDAR
QKALKDLLKWVLEGKIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIVKA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 35.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Bioactivity Probe target (PMID: 28248089)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_036344
Locus ID 22949
UniProt ID Q14914
Cytogenetics 9q31.3
RefSeq Size 1249
RefSeq ORF 987
Synonyms DIG-1; LTB4DH; PGR1; ZADH3
Summary This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2009
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "PTGR1" proteins (8)
SKU Description Size Price
PH306692 PTGR1 MS Standard C13 and N15-labeled recombinant protein (NP_036344) 10 ug
$3,360.00
LC415903 Lyophilized PTGR1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC431263 Lyophilized PTGR1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC431853 Lyophilized PTGR1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415903 Transient overexpression lysate of prostaglandin reductase 1 (PTGR1), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY431263 Transient overexpression lysate of prostaglandin reductase 1 (PTGR1), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY431853 Transient overexpression lysate of prostaglandin reductase 1 (PTGR1), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP328825 Recombinant protein of human prostaglandin reductase 1 (PTGR1), transcript variant 1, 20 µg 20 ug
$867.00

file-alt Citations

Mapping Novel Metabolic Nodes Targeted by Anti-Cancer Drugs that Impair Triple-Negative Breast Cancer Pathogenicity
Roberts, Yan, Bateman et al
ACS Chem. Biol. (2017)
AI Summary: OriGene’s recombinant PTGR1 protein was used in gel-based activity-based protein profiling assays to investigate how licochalcone A impairs triple-negative breast cancer cell pathogenicity by inhibiting PTGR1 enzyme activity.
Snippet: Gel-based ABPP methods were performed as previously described.43 Recombinant PTGR1 (0.1 μg) protein (Origene) was pretreated with DMSO or licochalcone A, respectively, for 1 h at 37 °C in an incubation volume of 50 μL of PBS and was subsequently treated ... All 3 versions Cite SaveSaving
Showing 1-1 of 1 papers.
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