AMBRA1 (NM_017749) Human Recombinant Protein
SKU
TP306255
Purified recombinant protein of Homo sapiens autophagy/beclin-1 regulator 1 (AMBRA1), 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 132.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Binding assay (PMID: 28362576) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_060219 |
| Locus ID | 55626 |
| UniProt ID | Q9C0C7 |
| Cytogenetics | 11p11.2 |
| RefSeq Size | 5034 |
| RefSeq ORF | 3624 |
| Synonyms | DCAF3; WDR94 |
| Summary | Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity).UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "AMBRA1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH306255 | AMBRA1 MS Standard C13 and N15-labeled recombinant protein (NP_060219) | 10 ug |
$3,360.00
|
|
| LC413575 | Lyophilized AMBRA1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413575 | Transient overexpression lysate of autophagy/beclin-1 regulator 1 (AMBRA1) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks
Schoenherr, Byron, Sandilands et al
Elife (2017) 6 DOI: 10.7554/eLife.23172
Schoenherr, Byron, Sandilands et al
Elife (2017) 6 DOI: 10.7554/eLife.23172
AI Summary: OriGene's recombinant Ambra1 protein was used to study Ambra1's binding to FAK, helping elucidate Ambra1's role in regulating Src/FAK signaling and cancer cell invasion.
Snippet: Briefly, overlapping 25-mer peptides of FAK were spotted onto nitrocellulose and incubated with recombinant Ambra1 (Origene, Herford, Germany)
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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