Gephyrin (GPHN) (NM_020806) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 83.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_065857 |
| Locus ID | 10243 |
| UniProt ID | Q9NQX3 |
| Cytogenetics | 14q23.3-q24.1 |
| RefSeq Size | 4318 |
| RefSeq ORF | 2307 |
| Synonyms | GEPH; GPH; GPHRYN; HKPX1; MOCODC |
| Summary | This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Gephyrin" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH305986 | GPHN MS Standard C13 and N15-labeled recombinant protein (NP_065857) | 10 ug |
$3,360.00
|
|
| LC402806 | Lyophilized GPHN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402806 | Transient overexpression lysate of gephyrin (GPHN), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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