CMPK1 (NM_016308) Human Recombinant Protein
SKU
TP304856L
Recombinant protein of human cytidine monophosphate (UMP-CMP) kinase 1, cytosolic (CMPK1), transcript variant 1, 1 mg
$9,200.00
6 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 25.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Enzyme activity (PMID: 26167664) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_057392 |
| Locus ID | 51727 |
| UniProt ID | P30085 |
| Cytogenetics | 1p33 |
| RefSeq Size | 2956 |
| RefSeq ORF | 684 |
| Synonyms | CK; CMK; CMPK; UMK; UMP-CMPK; UMPK |
| Summary | This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. provided by RefSeq, Feb 2012 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Pyrimidine metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Selective Phosphorylation of South and North-Cytidine and Adenosine Methanocarba-Nucleosides by Human Nucleoside and Nucleotide Kinases Correlates with Their Growth Inhibitory Effects on Cultured Cells
Sjuvarsson, Marquez, Eriksson
Nucleosides Nucleotides Nucleic Acids (2015) 34 (8), 544-64 DOI: 10.1080/15257770.2015.1031248
Sjuvarsson, Marquez, Eriksson
Nucleosides Nucleotides Nucleic Acids (2015) 34 (8), 544-64 DOI: 10.1080/15257770.2015.1031248
Cited by 12
AI Summary: OriGene products—specifically human recombinant cytosolic uridine-cytidine kinase 1 (CMPK1) and Human Erythrocyte Nucleoside Diphosphate Kinase (NDPK A/B)—were used as purified enzymes to evaluate the phosphorylation of methanocarba-nucleoside analogs in this study.
Snippet: Here we also used commercially available preparations of nucleotide kinases ie human recombinant cytosolic uridine-cytidine kinase 1 (CMPK 1) (OriGene Technologies, Inc.), and Human Erythrocyte Nucleoside Diphosphate Kinase (NDPK A/B (Nm23-H1/Nm23-H2 ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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