C4BPA (NM_000715) Human Recombinant Protein

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SKU
TP304738
Recombinant protein of human complement component 4 binding protein, alpha (C4BPA), 20 µg
  $867.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC204738 protein sequence
Red=Cloning site Green=Tags(s)

MHPPKTPSGALHRKRKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLGNCGPPPTLSFAAPMDITLTETR
FKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSC
SEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLL
GHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIH
CDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQK
NLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTP
SCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELV
NGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLP
NPEDVKMALEVYKLSLEIEQLELQRDSARQSTLDKEL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 61.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000706
Locus ID 722
UniProt ID P04003
Cytogenetics 1q32.2
RefSeq Size 2256
RefSeq ORF 1791
Synonyms C4BP; PRP
Summary This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. provided by RefSeq, Jul 2008
Protein Categories Immune system diseases, Secreated Proteins
Protein Pathways Complement and coagulation cascades
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Resources
Other "C4BPA" proteins (3)
SKU Description Size Price
PH304738 C4BPA MS Standard C13 and N15-labeled recombinant protein (NP_000706) 10 ug
$3,360.00
LC424544 Lyophilized C4BPA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424544 Transient overexpression lysate of complement component 4 binding protein, alpha (C4BPA) (as WB positive control) 100 ug
$436.00

file-alt Citations

Fucosylated C4b-binding protein α-chain, a novel serum biomarker that predicts lymph node metastasis in pancreatic ductal adenocarcinoma
Sogawa, Yamanaka, Takano et al
Oncol Lett (2021) 21 (2), 127 DOI: 10.3892/ol.2020.12388
Cited by 6
AI Summary: OriGene products, specifically the Human C4BPA cDNA clone and anti-C4BPA antibody, were used in this study to facilitate the detection and quantification of C4BPA in serum, supporting the development and validation of the lectin ELISA assay for identifying Fucosylated C4BPA as a novel biomarker for predicting lymph node metastasis in pancreatic ductal adenocarcinoma.
FigureFigureFigure
Showing 1-1 of 1 papers.
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