Eotaxin (CCL11) (NM_002986) Human Recombinant Protein

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SKU
TP304726
Purified recombinant protein of Human chemokine (C-C motif) ligand 11 (CCL11), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC204726 protein sequence
Red=Cloning site Green=Tags(s)

MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAK
DICADPKKKWVQDSMKYLDQKSPTPKP

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag Myc-DDK
Predicted MW 10.7 kDa
Concentration >0.05 µg/µL as determined by microplate Bradford method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002977
Locus ID 6356
UniProt ID P51671 Q6I9T4
Cytogenetics 17q12
RefSeq Size 925
RefSeq ORF 291
Synonyms SCYA11
Summary This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. provided by RefSeq, Sep 2014
Protein Categories Allergies and autoimmune diseases, Chemokines, Cytokines, Growth Factors, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Asthma, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway
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Other "Eotaxin" proteins (6)
SKU Description Size Price
LC401045 Lyophilized CCL11 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401045 Transient overexpression lysate of chemokine (C-C motif) ligand 11 (CCL11) (as WB positive control) 100 ug
$436.00
TP720904 Purified recombinant protein of Human chemokine (C-C motif) ligand 11 (CCL11) 10 ug
$260.00
TP723801 Purified recombinant protein of Human chemokine (C-C motif) ligand 11 (CCL11 / Eotaxin) 10 ug
$315.00
TP723802 Purified recombinant protein of Human chemokine (C-C motif) ligand 11 (CCL11 / Eotaxin) 10 ug
$315.00
TP762003 Purified recombinant protein of Human chemokine (C-C motif) ligand 11 (CCL11),Gly24-Pro97, with N-terminal His-Trx tag, expressed in E. coli, 50ug 50 ug
$270.00

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