GFAP (NM_002055) Human Recombinant Protein

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SKU
TP304548L
Recombinant protein of human glial fibrillary acidic protein (GFAP), transcript variant 1, 1 mg
  $9,200.00
5 Days*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC204548 protein sequence
Red=Cloning site Green=Tags(s)

MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNAGFKETRASER
AEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVE
RDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRE
LQEQLARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKH
EANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQ
DLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEV
IKESKQEHKDVM

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 49.7 kDa
Concentration >200 ug/mL as determined by Microplate Bradford Protein Assay method
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Bioactivity WB positive control (PMID: 29774780)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002046
Locus ID 2670
UniProt ID P14136
Cytogenetics 17q21.31
RefSeq Size 3097
RefSeq ORF 1296
Synonyms ALXDRD
Summary This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Oct 2008
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families ES Cell Differentiation/IPS
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Documents
Resources

file-alt Citations

Increased Levels of Circulating Glial Fibrillary Acidic Protein and Collapsin Response Mediator Protein-2 Autoantibodies in the Acute Stage of Spinal Cord Injury Predict the Subsequent Development of Neuropathic Pain
Hergenroeder, Redell, Choi et al
J. Neurotrauma (2018) 35 (21), 2530-2539 DOI: 10.1089/neu.2018.5675
AI Summary: In this study, OriGene's purified recombinant GFAP (TP304548) and CRMP2 (TP309080) proteins were used to detect autoantibodies in plasma samples from spinal cord injury patients, enabling the researchers to assess their association with the development of neuropathic pain.
Snippet: purchased from Thermo Fisher Scientific (Rockford, IL). Purified recombinant GFAP (TP304548) and CRMP2 (TP309080) proteins were obtained from OriGene (Rockville, MD). Human subjects: The protocol for the use of adult human subjects was reviewed and
Showing 1-1 of 1 papers.
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