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TMPRSS4 (NM_019894) Human Recombinant Protein

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SKU
TP303972
Recombinant protein of human transmembrane protease, serine 4 (TMPRSS4), transcript variant 1, 20 µg
Size:
20 ug 1 mg 100 ug
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC203972 protein sequence
Red=Cloning site Green=Tags(s)

MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHF
IPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETAC
RQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGGEE
ASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIE
FNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQV
IDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
KVSAYLNWIYNVWKAEL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 48 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Bioactivity Cell treatment (PMID: 29529050)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_063947
Locus ID 56649
UniProt ID Q9NRS4
Cytogenetics 11q23.3
RefSeq Size 3549
RefSeq ORF 1311
Synonyms CAP2; CAPH2; MT-SP2; TMPRSS3
Summary This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Peptidases, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Protease, Transmembrane
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Other "TMPRSS4" proteins (11)
SKU Description Size Price
PH302384 TMPRSS4 MS Standard C13 and N15-labeled recombinant protein (NP_899070) 10 ug
$3,360.00
PH303972 TMPRSS4 MS Standard C13 and N15-labeled recombinant protein (NP_063947) 10 ug
$3,360.00
PH324725 TMPRSS4 MS Standard C13 and N15-labeled recombinant protein (NP_001077416) 10 ug
$3,360.00
LC405242 Lyophilized TMPRSS4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC412678 Lyophilized TMPRSS4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC432994 Lyophilized TMPRSS4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY405242 Transient overexpression lysate of transmembrane protease, serine 4 (TMPRSS4), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY412678 Transient overexpression lysate of transmembrane protease, serine 4 (TMPRSS4), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY432994 Transient overexpression lysate of transmembrane protease, serine 4 (TMPRSS4), transcript variant 5 (as WB positive control) 100 ug
$436.00
TP302384 Recombinant protein of human transmembrane protease, serine 4 (TMPRSS4), transcript variant 2, 20 µg 20 ug
$867.00
TP324725 Purified recombinant protein of Homo sapiens transmembrane protease, serine 4 (TMPRSS4), transcript variant 3, 20 µg 20 ug
$867.00

file-alt Citations

Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury
Valero-Jiménez, Zúñiga, Cisneros et al
PLoS ONE (2018) 13 (3), e0192963 DOI: 10.1371/journal.pone.0192963
AI Summary: OriGene’s human recombinant TMPRSS4 protein (TP303972) was used to treat cells in vitro, enabling the authors to assess the effects of TMPRSS4 on cell growth and fibrotic response in their study of idiopathic pulmonary fibrosis.
Snippet: After 24 h, the medium was replaced by serum-free medium alone or with human recombinant TMPRSS4 [Origene, TP303972 (0.1, 1, 10 and 100 ng/mL)], and the cells were maintained in culture for 48 or 96 h. Cell growth was determined using the cell proliferation Cached
FigureFigureFigure
Showing 1-1 of 1 papers.
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