TRIM25 (NM_005082) Human Recombinant Protein
$2,508.00
5 Days*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 70.8 kDa |
| Concentration | >0.1 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005073 |
| Locus ID | 7706 |
| UniProt ID | Q14258 |
| Cytogenetics | 17q22 |
| RefSeq Size | 5744 |
| RefSeq ORF | 1890 |
| Synonyms | EFP; RNF147; Z147; ZNF147 |
| Summary | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. provided by RefSeq, Jul 2008 |
| Protein Categories | Enzyme: Ligase, Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | RIG-I-like receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
GLUL mediates FOXO3 O-GlcNAcylation to regulate the osteogenic differentiation of BMSCs and senile osteoporosis
Zhang, Qi, Li et al
Cell Death Differ (2025)
Zhang, Qi, Li et al
Cell Death Differ (2025)
Cited by 19
AI Summary: OriGene products—TRIM25 (NM_005082) Human Recombinant Protein, Glutamine Synthetase (GLUL) (NM_002065) Human Recombinant Protein, and UAP1 (NM_003115) Human Recombinant Protein—were used in this study to investigate the molecular interactions and mechanisms underlying GLUL-mediated regulation of osteogenic differentiation in BMSCs relevant to senile osteoporosis.
Snippet: Chloroquine (HY-17589A) were obtained from MedChemExpress LLC (New Jersey, USA). TRIM25 (NM_005082) Human Recombinant Protein, Glutamine Synthetase (GLUL) (NM_002065) Human Recombinant Protein and UAP1 (NM_003115) Human Recombinant Protein were obtained from OriGene (Maryland, USA). Biacore Series S Sensor Chip CM5 were obtained from Cytiva (Washington, D.C. USA)
Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy
Zhang, Li, Li et al
Adv Sci (Weinh) (2025)
Zhang, Li, Li et al
Adv Sci (Weinh) (2025)
Cited by 3
AI Summary: OriGene’s TRIM25 protein (catalog number TP303757) was used in binding assays to investigate the molecular interactions between TRIM25, PKMYT1, and Meisoindigo, supporting the study’s discovery of Meisoindigo as a molecular glue promoting PKMYT1 degradation in chronic myeloid leukemia therapy.
An anti-influenza A virus microbial metabolite acts by degrading viral endonuclease PA
Zhao, Wang, Pang et al
Nat Commun (2022) 13 (1), 2079 DOI: 10.1038/s41467-022-29690-x
Zhao, Wang, Pang et al
Nat Commun (2022) 13 (1), 2079 DOI: 10.1038/s41467-022-29690-x
Cited by 64
AI Summary: In this study, the pCMV6-SIRT7 plasmid from OriGene Technologies was used to investigate the molecular mechanism by which the anti-influenza compound APL-16-5 induces degradation of the viral PA protein.
Snippet: chased from Youbio Biological Technology Co., Ltd. PA-luc was generated by cloning the nano-luciferase gene into the C-terminal of the wild-type PA protein. The pCMV6-SIRT7 plasmid was purchased from OriGene Technologies, Inc. The following antibodies were used for western blotting or immunoprecipitation: rabbit anti-PA (1:1000, GTX125932), anti-NP (1:1000, GTX125989), anti-PB1 (1:1000, GTX125923
Showing 1-3 of 3 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
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