Lin28 (LIN28A) (NM_024674) Human Recombinant Protein

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SKU
TP303397
Purified recombinant protein of Homo sapiens lin-28 homolog (LIN28), 20 µg
  $867.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC203397 protein sequence
Red=Cloning site Green=Tags(s)

MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPV
DVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCY
NCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 22.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_078950
Locus ID 79727
UniProt ID Q9H9Z2
Cytogenetics 1p36.11
RefSeq Size 4014
RefSeq ORF 627
Synonyms CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
Summary This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. provided by RefSeq, Sep 2015
Protein Categories Growth Factors, Intracellular Proteins
Protein Families Transcription Factors
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Other "Lin28" proteins (3)
SKU Description Size Price
PH303397 LIN28A MS Standard C13 and N15-labeled recombinant protein (NP_078950) 10 ug
$3,360.00
LC411135 Lyophilized LIN28A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411135 Transient overexpression lysate of lin-28 homolog (LIN28) (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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