CIAO2A (NM_032231) Human Recombinant Protein

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SKU
TP303357
Recombinant protein of human family with sequence similarity 96, member A (FAM96A), transcript variant 1, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC203357 protein sequence
Red=Cloning site Green=Tags(s)

MQRVSGLLSWTLSRVLWLSGLSEPGAARQPRIMEEKALEVYDLIRTIRDPEKPNTLEELEVVSESCVEVQ
EINEEEYLVIIRFTPTVPHCSLATLIGLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVA
AAMENPNLREIVEQCVLEPD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 18.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_115607
Locus ID 84191
UniProt ID Q9H5X1
Cytogenetics 15q22.31
RefSeq Size 1114
RefSeq ORF 480
Synonyms CIA2A; FAM96A
Summary Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227).UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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Other "CIAO2A" proteins (3)
SKU Description Size Price
PH303357 FAM96A MS Standard C13 and N15-labeled recombinant protein (NP_115607) 10 ug
$3,360.00
LC410258 Lyophilized FAM96A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410258 Transient overexpression lysate of family with sequence similarity 96, member A (FAM96A), transcript variant 1 (as WB positive control) 100 ug
$436.00

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