SERPINB3 (NM_006919) Human Recombinant Protein

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SKU
TP302683M
Recombinant protein of human serpin peptidase inhibitor, clade B (ovalbumin), member 3 (SERPINB3), 100 µg
  $2,508.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC202683 protein sequence
Red=Cloning site Green=Tags(s)

MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKA
ATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAP
EESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSI
QMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRV
DLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVV
GFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 44.4 kDa
Concentration >0.1 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_008850
Locus ID 6317
UniProt ID P29508
Cytogenetics 18q21.33
RefSeq Size 1793
RefSeq ORF 1170
Synonyms HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; SSCA1; T4-A
Summary May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Secreted Protein
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Documents
Resources

file-alt Citations

The kinetic profile and clinical implication of SCC-Ag in squamous cervical cancer patients undergoing radical hysterectomy using the Simoa assay: a prospective observational study
Ye, Sun, Kang et al
BMC Cancer (2020) 20 (1), 138 DOI: 10.1186/s12885-020-6630-0
Cited by 17
AI Summary: OriGene's recombinant human SCC-Ag (TP302683) was used to generate the calibration curve for the Simoa assay, enabling accurate measurement of SCC-Ag levels in cervical cancer patients throughout the study.
Snippet: To generate the calibration curve, recombinant human SCC-Ag (TP302683, Origene, USA) was serially diluted in the sample diluent, and the final concentrations of the 8 calibrators (calibrators A- H) in the assay were 0.049 to 50 ng/mL;- To generate the calibration curve, recombinant human SCC-Ag (TP302683, Origene, USA) was serially diluted in the sample diluent, and the final concentrations of the 8 calibrators (calibrators A- H) in the assay were 0.049 to 50 ng/mL
Showing 1-1 of 1 papers.
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