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FRA1 (FOSL1) (NM_005438) Human Recombinant Protein

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SKU
TP302104
Recombinant protein of human FOS-like antigen 1 (FOSL1), 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Recombinant protein was produced with TrueORF clone, RC202104. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 29.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005429
Locus ID 8061
UniProt ID P15407
Cytogenetics 11q13.1
RefSeq Size 1759
RefSeq ORF 813
Synonyms FRA; fra-1; FRA1
Summary The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2014
Protein Categories Cytokines, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Wnt signaling pathway
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Documents
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Other "FRA1" proteins (1)
SKU Description Size Price
PH302104 FOSL1 MS Standard C13 and N15-labeled recombinant protein (NP_005429) 10 ug
$3,360.00

file-alt Citations

Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
Nat Commun (2025) 16 (1), 4055 DOI: 10.1038/s41467-025-59109-2
Cited by 2
AI Summary: OriGene products contributed to this study by providing recombinant proteins—ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), and FOS2L (TP760114)—used in functional assays to investigate gene regulatory mechanisms underlying pancreatic cancer risk.
Snippet: ELF2 (TP760288), ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) proteins were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
FigureFigureFigure
Allelic effects on KLHL17 expression likely mediated by JunB/D underlie a PDAC GWAS signal at chr1p36.33
Connelly, Hullin, Abdolalizadeh et al
medRxiv (2024)
Snippet: ELF3 (TP300631), ELF4 (TP761826), JUNB (TP303595), JUND (TP316958 4), c-FOS (TP760257), FOS1L (TP302104), FOSB (TP762032), FOS2L (TP760114) protein were purchased from Origene (Rockville, MD). c-JUN was purchased from Abcam (Waltham, MA) (ab84134). ELF5, which has negligible expression in the pancreas, was not tested
FigureFigureFigure
Showing 1-2 of 2 papers.
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