uPA (PLAU) (NM_002658) Human Recombinant Protein
SKU
TP302083
Recombinant protein of human plasminogen activator, urokinase (PLAU), transcript variant 1, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 46.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002649 |
| Locus ID | 5328 |
| UniProt ID | P00749 |
| Cytogenetics | 10q22.2 |
| RefSeq Size | 2395 |
| RefSeq ORF | 1293 |
| Synonyms | ATF; BDPLT5; QPD; u-PA; UPA; URK |
| Summary | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016 |
| Protein Categories | Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protease |
| Protein Pathways | Complement and coagulation cascades |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "uPA" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302083 | PLAU MS Standard C13 and N15-labeled recombinant protein (NP_002649) | 10 ug |
$3,360.00
|
|
| LC400942 | Lyophilized PLAU HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400942 | Transient overexpression lysate of plasminogen activator, urokinase (PLAU), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP720654 | Purified recombinant protein of Human plasminogen activator, urokinase (PLAU), transcript variant 1 | 10 ug |
$340.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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