PEX5 (NM_000319) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 69.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000310 |
| Locus ID | 5830 |
| UniProt ID | P50542 |
| Cytogenetics | 12p13.31 |
| RefSeq Size | 3190 |
| RefSeq ORF | 1893 |
| Synonyms | PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5 |
| Summary | The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Oct 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "PEX5" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302062 | PEX5 MS Standard C13 and N15-labeled recombinant protein (NP_000310) | 10 ug |
$3,360.00
|
|
| LC424800 | Lyophilized PEX5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC427361 | Lyophilized PEX5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC427362 | Lyophilized PEX5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424800 | Transient overexpression lysate of peroxisomal biogenesis factor 5 (PEX5), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY427361 | Transient overexpression lysate of peroxisomal biogenesis factor 5 (PEX5), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY427362 | Transient overexpression lysate of peroxisomal biogenesis factor 5 (PEX5), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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