PEX5 (NM_000319) Human Recombinant Protein

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SKU
TP302062
Recombinant protein of human peroxisomal biogenesis factor 5 (PEX5), transcript variant 2, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC202062 protein sequence
Red=Cloning site Green=Tags(s)

MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASEDELVAEFLQDQ
NAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDW
SQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKL
ANSEFLKFVRQIGEGQVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSA
IELQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLF
EAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRD
WLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLF
NLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCIN
LGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLP
Q

SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 69.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000310
Locus ID 5830
UniProt ID P50542
Cytogenetics 12p13.31
RefSeq Size 3190
RefSeq ORF 1893
Synonyms PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5
Summary The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Oct 2008
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "PEX5" proteins (7)
SKU Description Size Price
PH302062 PEX5 MS Standard C13 and N15-labeled recombinant protein (NP_000310) 10 ug
$3,360.00
LC424800 Lyophilized PEX5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC427361 Lyophilized PEX5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC427362 Lyophilized PEX5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424800 Transient overexpression lysate of peroxisomal biogenesis factor 5 (PEX5), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY427361 Transient overexpression lysate of peroxisomal biogenesis factor 5 (PEX5), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY427362 Transient overexpression lysate of peroxisomal biogenesis factor 5 (PEX5), transcript variant 3 (as WB positive control) 100 ug
$436.00

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