KAP1 (TRIM28) (NM_005762) Human Recombinant Protein
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 88.4 kDa |
| Concentration | >0.1 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005753 |
| Locus ID | 10155 |
| UniProt ID | Q13263 |
| Cytogenetics | 19q13.43 |
| RefSeq Size | 2989 |
| RefSeq ORF | 2505 |
| Synonyms | KAP1; PPP1R157; RNF96; TF1B; TIF1B |
| Summary | The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Protein Kinase, Stem cell - Pluripotency, Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "KAP1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301205 | TRIM28 MS Standard C13 and N15-labeled recombinant protein (NP_005753) | 10 ug |
$3,360.00
|
|
| LC417086 | Lyophilized TRIM28 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY417086 | Transient overexpression lysate of tripartite motif-containing 28 (TRIM28) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
SMURF2/USP7-mediated ubiquitination of KAP1 controls its SUMO E3 ligase activity and chromatin regulation
Boutros‐Suleiman, Nambiar, Shah et al
bioRxiv (2025)
Boutros‐Suleiman, Nambiar, Shah et al
bioRxiv (2025)
Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways
Gilmore-Hebert, Ramabhadran, Stern
Mol Cancer Res (2010) 8 (10), 1388-98 DOI: 10.1158/1541-7786.MCR-10-0042
Gilmore-Hebert, Ramabhadran, Stern
Mol Cancer Res (2010) 8 (10), 1388-98 DOI: 10.1158/1541-7786.MCR-10-0042
AI Summary: In this study, OriGene products—including the ERBB4 expression plasmid (RC200003) and ERBB4 shRNA (TG311019)—were used to manipulate ERBB4 levels in cells, enabling the authors to investigate the molecular interactions and functional consequences of ErbB4 and Kap1 in linking growth factor and DNA damage response pathways.
Showing 1-2 of 2 papers.
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