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MRPS34 (NM_023936) Human Recombinant Protein

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SKU
TP300834
Recombinant protein of human mitochondrial ribosomal protein S34 (MRPS34), nuclear gene encoding mitochondrial protein, 20 µg
Size:
20 ug 1 mg 100 ug
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC200834 protein sequence
Red=Cloning site Green=Tags(s)

MARKKVRPRLIAELARRVRALREQLNRPRDSQLYAVDYETLTRPFSGRRLPVRAWADVRRESRLLQLLGR
LPLFGLGRLVTRKSWLWQHDEPCYWRLTRVRPDYTAQNLDHGKAWGILTFKGKTESEAREIEHVMYHDWR
LVPKHEEEAFTAFTPAPEDSLASVPYPPLLRAMIIAERQKNGDTSTEEPMLNVQRIRMEPWDYPAKQEDK
GRAKGTPV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 25.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_076425
Locus ID 65993
UniProt ID P82930
Cytogenetics 16p13.3
RefSeq Size 1020
RefSeq ORF 654
Synonyms COXPD32; MRP-S12; MRP-S34; MRPS12
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014
Protein Categories Intracellular Proteins
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Other "MRPS34" proteins (3)
SKU Description Size Price
PH300834 MRPS34 MS Standard C13 and N15-labeled recombinant protein (NP_076425) 10 ug
$3,360.00
LC411441 Lyophilized MRPS34 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411441 Transient overexpression lysate of mitochondrial ribosomal protein S34 (MRPS34), nuclear gene encoding mitochondrial protein (as WB positive control) 100 ug
$436.00

file-alt Citations

The role of autoproteolysis and mitoribosomal proteins in the regulation of the mitochondrial LACTB tumor suppressor
Escudeiro-Lopes, González-Morena, Baudysova et al
EMBO Reports (2026)
AI Summary: In this study, OriGene's Recombinant MRPS34 protein (TP300834) was used to investigate the regulatory interaction between MRPS34 and the mitochondrial tumor suppressor LACTB, helping to elucidate how MRPS34 promotes LACTB autoproteolysis and inactivation in cancer cells.
Snippet: Quick Change XL Site-Directed Mutagenesis Kit Agilent Technologies Recombinant MRPS34 protein OriGene TP300834 Granzyme B inhibitor (Z-AAD-CMK) Sigma-Aldrich 368050
The role of autoproteolysis and mitoribosomal proteins in regulation of mitochondrial LACTB tumor suppressor
Escudeiro-Lopes, González-Morena, Baudysova et al
bioRxiv (2025)
AI Summary: OriGene contributed to this study by providing recombinant proteins for MRPS34 (TP300834), GAPDH (TP302309), COQ6 (TP760736), HSBP1 (TP301399), ASCL3 (TP320042), and TOMM20 (TP310746), which were used to investigate the molecular mechanisms regulating the mitochondrial tumor suppressor LACTB.
Snippet: Recombinant proteins for MRPS34 (TP300834), GAPDH 171 (TP302309), COQ6 (TP760736), HSBP1 (TP301399), ASCL3 (TP320042) and TOMM20 172 (TP310746) were purchased from OriGene. Recombinant protein for HIGD1A (ab125988) was 173 purchased from Abcam. Proteins were aliquoted and stored at -80ºC
Showing 1-2 of 2 papers.
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