PFKP (NM_002627) Human Recombinant Protein
$737.00
5 Days*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 85.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Cell treatment (PMID: 28467929) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002618 |
| Locus ID | 5214 |
| UniProt ID | Q01813 |
| Cytogenetics | 10p15.2 |
| RefSeq Size | 2657 |
| RefSeq ORF | 2352 |
| Synonyms | ATP-PFK; PFK-C; PFK-P; PFKF |
| Summary | This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2016 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PFKP" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300673 | PFKP MS Standard C13 and N15-labeled recombinant protein (NP_002618) | 10 ug |
$3,360.00
|
|
| LC400932 | Lyophilized PFKP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400932 | Transient overexpression lysate of phosphofructokinase, platelet (PFKP) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism
Calvier, Chouvarine, Legchenko et al
Cell Metab. (2017) 25 (5), 1118-1134.e7 DOI: 10.1016/j.cmet.2017.03.011
Calvier, Chouvarine, Legchenko et al
Cell Metab. (2017) 25 (5), 1118-1134.e7 DOI: 10.1016/j.cmet.2017.03.011
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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