GDI2 (NM_001494) Human Recombinant Protein
SKU
TP300596M
Recombinant protein of human GDP dissociation inhibitor 2 (GDI2), transcript variant 1, 100 µg
$2,950.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 50.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001485 |
| Locus ID | 2665 |
| UniProt ID | P50395 |
| Cytogenetics | 10p15.1 |
| RefSeq Size | 2441 |
| RefSeq ORF | 1335 |
| Synonyms | HEL-S-46e; RABGDIB |
| Summary | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
Reviews
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Resources
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Citations
Adipose tissue depot-specific intracellular and extracellular cues contributing to insulin resistance in obese individuals
Guzmán-Ruiz, Tercero-Alcázar, Rabanal-Ruiz et al
FASEB J. (2020)
Guzmán-Ruiz, Tercero-Alcázar, Rabanal-Ruiz et al
FASEB J. (2020)
AI Summary: OriGene contributed to this study by providing the DsRed-GDI2 plasmid (NM_001494), which was used for overexpression experiments to investigate the role of GDI2 in adipocyte function related to insulin resistance.
Snippet: For overexpression studies, 3T3-L1 adipocytes (D6) on 150-mm Petri dishes were electroporated using either a DsRed or CFP empty vectors or containing the coding sequence of the GDP dissociation inhibitor of Rab proteins, GDI2 (NM_001494;Origene, Madrid, Spain) (DsRed-GDI2) (50 µg), following our established procedures.22,26 Thereafter, cells were cultured for 48 hours, and then, processed for confocal microscopy and functional studies (see below)
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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