ID3 (NM_002167) Human Recombinant Protein
SKU
TP300583
Recombinant protein of human inhibitor of DNA binding 3, dominant negative helix-loop-helix protein (ID3), 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 12.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002158 |
| Locus ID | 3399 |
| UniProt ID | Q02535 |
| Cytogenetics | 1p36.12 |
| RefSeq Size | 1252 |
| RefSeq ORF | 357 |
| Synonyms | bHLHb25; HEIR-1 |
| Summary | The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. provided by RefSeq, Aug 2011 |
| Protein Categories | Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
| Protein Pathways | TGF-beta signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ID3" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300583 | ID3 MS Standard C13 and N15-labeled recombinant protein (NP_002158) | 10 ug |
$3,360.00
|
|
| LC419492 | Lyophilized ID3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419492 | Transient overexpression lysate of inhibitor of DNA binding 3, dominant negative helix-loop-helix protein (ID3) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
PCB153-Induced Overexpression of ID3 Contributes to the Development of Microvascular Lesions
Das, Felty
PLoS ONE (2014) 9 (8), e104159 DOI: 10.1371/journal.pone.0104159
Das, Felty
PLoS ONE (2014) 9 (8), e104159 DOI: 10.1371/journal.pone.0104159
Cited by 26
AI Summary: OriGene’s recombinant ID3 protein (GST–Myc-DDK/FLAG, TP300583) was used in in vitro kinase assays to study how PCB153 influences ID3 phosphorylation and its role in microvascular lesion development.
Snippet: In vitro kinase assay. FLAG-ID3 in vitro kinase assay: Active recombinant human Pyk2 kinase (0.1 µg/µl, Signal Chem) was added with ATP (10 mM, Signal Chem), ID3 protein (Recombinant protein with GST–Myc-DDK/FLAG, TP300583, OriGene), and incubated 37 ... Cite SaveSaving
Showing 1-1 of 1 papers.
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