CPT2 (NM_000098) Human Recombinant Protein
SKU
TP300484M
Recombinant protein of human carnitine palmitoyltransferase 2 (CPT2), nuclear gene encoding mitochondrial protein, 100 µg
$2,508.00
5 Days*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 71.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000089 |
| Locus ID | 1376 |
| UniProt ID | P23786 |
| Cytogenetics | 1p32.3 |
| RefSeq Size | 3110 |
| RefSeq ORF | 1974 |
| Synonyms | CPT1; CPTASE; IIAE4 |
| Summary | The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Fatty acid metabolism, PPAR signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Mitochondrial SIRT2-mediated CPT2 deacetylation prevents diabetic cardiomyopathy by impeding cardiac fatty acid oxidation
Guo, Zhang, Wen et al
Int J Biol Sci (2025) 21 (2), 725-744 DOI: 10.7150/ijbs.102834
Guo, Zhang, Wen et al
Int J Biol Sci (2025) 21 (2), 725-744 DOI: 10.7150/ijbs.102834
Cited by 18
AI Summary: In this study, OriGene’s Myc/Flag-CPT2 (#TP300484) was used in GST pull-down assays to investigate the interaction between SIRT2 and CPT2, helping to elucidate the molecular mechanism by which SIRT2 regulates cardiac fatty acid oxidation in diabetic cardiomyopathy.
Snippet: is buffer, boiled with 1✕buffer, and analyzed by western blotting [27]. GST PULL-DOWN The GST-SIRT2 fusion protein was purchased from Proteintech (#Ag7556), while Myc/Flag-CPT2 was purchased from ORIGENE (#TP300484), and the GST-WT fusion protein was purchased from ABclonal (#RPT0001LQ). Equal amounts of GST fusion proteins (conjugated on beads) were incubated with 1 ml of cell lysate (NP40 co
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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