SND1 (NM_014390) Human Recombinant Protein

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SKU
TP300059
Recombinant protein of human staphylococcal nuclease and tudor domain containing 1 (SND1), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC200059 protein sequence
Red=Cloning site Green=Tags(s)

MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDA
KDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMR
ANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRA
LLLPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHP
NGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQV
LNADAIVVKLNSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD
YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNG
KGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIEC
PRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHIDGANLSVLLVEHALSKV
HFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQD
VETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNRE
VLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV
TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 101.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_055205
Locus ID 27044
UniProt ID Q7KZF4
Cytogenetics 7q32.1
RefSeq Size 3522
RefSeq ORF 2730
Synonyms p100; TDRD11; Tudor-SN
Summary This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). provided by RefSeq, Jul 2016
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Transcription Factors
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Other "SND1" proteins (3)
SKU Description Size Price
PH300059 SND1 MS Standard C13 and N15-labeled recombinant protein (NP_055205) 10 ug
$3,360.00
LC415313 Lyophilized SND1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415313 Transient overexpression lysate of staphylococcal nuclease and tudor domain containing 1 (SND1) (as WB positive control) 100 ug
$436.00

file-alt Citations

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9
Schmidt, Ganskih, Wei et al
Cell (2023) 186 (22), 4834-4850.e23 DOI: 10.1016/j.cell.2023.09.002
Cited by 54
AI Summary: OriGene’s SND1 recombinant protein (TP300059) was used in this study to investigate the interaction between SND1 and SARS-CoV-2 RNA, helping to demonstrate SND1’s role in promoting viral RNA synthesis.
Snippet: dPCR EvaGreen Supermix BioRad 1864034 QX200 droplet generation oil for EvaGreen BioRad 1864006 2′-deoxythymidine-3′,5′-bisphosphate Biosynth NT09781 SND1 recombinant protein Origene TP300059 NSP9 recombinant protein Abcam ab289608 ------------------------- Critical commercial assays ------------------------- Pierce BCA Protein Assay Kit Thermo Scientific C
FigureFigureFigure
Showing 1-1 of 1 papers.
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