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ACTN2 (NM_001103) Human Recombinant Protein

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SKU
LP308531
Lyophilized purified recombinant protein of Human actinin, alpha 2 (ACTN2), 20ug
Size:
20 ug
Formulation:
Lyophilized Liquid
  $867.00
2 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC208531, encoding the full-length of ACTN2
Tag C-terminal Myc-DDK tag
Predicted MW 103.7 kDa
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 μm filtered solution of 25 mM Tris-HCl, 100 mM glycine, 50 mM NaCl, 8% trehalose, pH 7.3
Reconstitution Method It is not recommended to reconstitute to a concentration less than 200 μg/mL in ddH2O.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Stability Stored at -20 to -70 ℃ for 1 year and avoid repeated freeze-thaw cycles after receipt; After reconstitution, the protein can be stored longer at -20 to -70 ℃, with aliquoting for single use recommended to prevent repeated freeze-thaw.
Shipping Blue Ice
Reference Data
RefSeq NP_001094
Locus ID 88
UniProt ID P35609
Cytogenetics 1q43
RefSeq Size 4181
RefSeq ORF 2682
Synonyms CMD1AA; CMH23; MPD6; MYOCOZ
Summary Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2013
Protein Categories Cardiovascular diseases, Intracellular Proteins
Protein Pathways Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Systemic lupus erythematosus, Tight junction
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Other "ACTN2" proteins (3)
SKU Description Size Price
PH308531 ACTN2 MS Standard C13 and N15-labeled recombinant protein (NP_001094) 10 ug
$3,360.00
LC420189 Lyophilized ACTN2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY420189 Transient overexpression lysate of actinin, alpha 2 (ACTN2) (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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