LYVE-1 Mouse Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | Insect |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 45 kDa |
| Purity | >95% by SDS-PAGE and visualised by silver stain |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Lyophilized protein Buffer System: PBS Stabilizer: None |
| Endotoxin | < 0.1 ng per µg of VEGF-C |
| Reconstitution Method | Lyophilized sLYVE-1 is soluble in water and most aqueous buffers. The lyophilised sLYVE-1 should be reconstituted in PBS or medium to a concentration not lower than 50 µg/ml. |
| Preparation | Lyophilized protein |
| Protein Description | Recombinant Mouse Soluble LYVE-1-His. A DNA sequence encoding the extracellular domain of mouse LYVE-1 (Met1 - Gly228) was fused to a C-terminal His -tag (6xHis) and expressed in insect cells. Based on N-terminal sequence analysis, the primary structure of recombinant mature sLYVE-1 starts at Ala24. Result by N-terminal sequencing: ADLVQDLS Length: 211 amino acids. |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_444477 |
| Locus ID | 114332 |
| UniProt ID | Q8BHC0 |
| Cytogenetics | 7 E3 |
| Synonyms | LYVE1, CRSBP-1, CRSBP1, HAR, XLKD1 |
| Summary | Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.UniProtKB/Swiss-Prot Function |
| Protein Categories | Membrane Proteins |
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