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VEGF-C / Flt4-L Rat Protein

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SKU
DA3519X
VEGF-C / Flt4-L rat recombinant protein, 20 µg
Size:
20 ug
  $485.00
2 Weeks*
Bulk/Customize

Other products for "Vegfc or NM_053653"

Specifications
Specifications
Product Data
Species Rat
Expression Host Insect
Expression cDNA Clone or AA Sequence
Protein Sequence
DTVKLAAAHY NTEILKSIDN EWRKTQCMPR EVCIDVGKEF GAATNTFFKP PCVSVYRCGG CCNSEGLQCM NTSTGYLSKT LFEITVPLSQ GPKPVTISFA NHTSCRCMSK LDVYRQVHSI IHHHHHH
Predicted MW 15-20 kDa
Purity >90% pure by SDS-PAGE and visualised by silver stain
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized purified protein
Buffer System: 50 mM Acetic Acid
Stabilizer: BSA
Bioactivity Biological: Determined (i) by the ability to induce VEGFR-3/FLT-4 receptor phosphorylation in PAEC/VEGFR-3 cells and (ii) the VEGF-C-induced proliferation of primary human dermal lymphatic endothelial cells (HDLEC).
Endotoxin < 0.1 ng per µg of VEGF-C
Reconstitution Method The lyophilized VEGF-C is soluble in water and most aqueous buffers.
Restore in PBS or medium to a concentration not lower than 50 µg/ml.
Preparation Lyophilized purified protein
Protein Description The recombinant Rat VEGF-C contains 115 amino acids residues and was fused to a His-tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 15-20 kDa protein in SDS-PAGE under reducing conditions.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_446105
Locus ID 114111
UniProt ID O35757
Cytogenetics 16p11
Synonyms VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein, Flt4 ligand
Summary platelet-derived growth factor/vascular derived growth factor (PDGF/VEGF); active in angiogenesis and endothelial cell growth RGD, Feb 2006
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Documents
Resources

file-alt Citations

Vascular endothelial growth factor C-induced lymphangiogenesis decreases tumor interstitial fluid pressure and tumor
Hofmann, Pflanzer, Zoller et al
Transl Oncol (2013) 6 (4), 398-404 DOI: 10.1593/tlo.13274
Cited by 16
AI Summary: OriGene products contributed to this study by providing the VEGF-C cDNA (OriGene, Cat# SC315409), which was used to induce lymphangiogenesis and investigate its effects on tumor interstitial fluid pressure and growth in a xenograft mouse model.
Showing 1-1 of 1 papers.
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