KITLG / SCF (His-tag) Human Protein
KITLG / SCF (His-tag) human recombinant protein, 50 µg
|Description||KITLG / SCF (His-tag) human recombinant protein, 50 µg|
|Predicted MW||18.4 kDa|
|Purity||>95% 95% by SDS-PAGE and visualised by silver stain|
|Buffer||Presentation State: Purified
State: Lyophilized purified protein
Buffer System: PBS, pH 7.4, without stabilizer
|Bioactivity||Biological: Measured in a cell proliferation assay using TF 1 human erythroleukemic cells [Kitamura T et al, J Cell Physiol, 1989]. The ED50 for this effect is typically 1‑5 ng/ml.|
|Endotoxin||< 0.1 ng per µg of SCF|
|Reconstitution||Restore in water to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.|
|Preparation||Lyophilized purified protein|
|Protein Description||Recombinant Human Stem Cell Factor (SCF) His-tag.
Soluble Stem Cell Factor (SCF), a 18.4kDa protein consisting of 165 amino acid residues (Glu26-Ala190) and fused to a C-terminal His-tag (6x His).
|Storage||Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Synonyms||DCUA; DFNA69; FPH2; FPHH; Kitl; KL-1; MGF; SCF; SF; SHEP7; SLF|
|Summary||This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]|
|Protein Families||Druggable Genome, Transmembrane|
|Protein Pathways||Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer|