OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

HIV-2 (gp36) Protein

Be the first to review this product
SKU
BIN177
HIV-2 gp36 recombinant protein, 1 mg
Size:
1 mg
  $1,800.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Expression Host E. coli
Concentration lot specific
Purity DEAE Sepharose chromatography.
Presentation State Purified
Buffer Presentation State: Purified
State: Liquid purified fraction (>95% pure by 10% PAGE coomassie staining).
Buffer System: 50 mM Tris HCl, 8 M Urea, pH 8.4, containing no preservatives
Preparation Liquid purified fraction (>95 % pure by 10% PAGE coomassie staining).
Recommended Dilution Suitable for use in ELISA and Western blots.
Protein Description Human Immunodeficiency Virus Type 2 (HIV-2) envelope, gp36 recombinant. Contains the HIV-2 immunodominant region of envelope gp36. Not full-length gp36. Does not contain a fusion partner. Immunoreactive with HIV-2 positive sera.
Storage Store the antigen at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid multiple freeze/thaw cycles.
Stability Shelf life: six months from despatch.
Shipping Blue Ice
Reference Data
Synonyms HIV2, Human immunodeficiency virus type 2
Summary HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. Little is known about the best approach to the clinical treatment and care of patients infected with HIV2. Some drugs used to treat HIV1 are ineffective.
HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2.
The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response. Hence, most licensed diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific antibodies. It is becoming important to differentiate between single infection with either HIV1 or HIV2 and dual infection.
Protein Families Suitable for use in ELISA and Western blots.
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products