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Collagen type IV Bovine Protein

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SKU
RA008
Bovine Collagen Type IV
Size:
500 ug
  $585.00
5 Days*
Bulk/Customize

Other products for "COL4A1 or NM_001303110"

Specifications
Specifications
Product Data
Species Bovine
Protein Source Placenta
Concentration 1.0 mg/ml by nanodrop at 205 nm
Purity Bovine Collagen Type IV has been prepared from Bovine Placenta and is chromatographically and immunologically pure.  Bovine Collagen Type IV reacts with anti-Collagen Type IV.  Reaction with Rockland’s anti-Collagen I, II, III, V or VI is negligible.
Buffer 0.5 M Acetic Acid
Preparation Liquid (sterile filtered) purified Ig fraction.
Recommended Dilution ELISA,Immunohistochemistry,Western Blot
Protein Description This product has been prepared from Bovine Placenta and reacts with anti-Collagen Type IV. Reaction with anti-Collagen I, II, III, V or VI is negligible (typically less than 1% cross reactivity was detected by ELISA).
Note Bovine Collagen Type IV has been tested in SDS-Page and can be utilized as a control or standard reagent in Western Blotting and ELISA experiments.
Storage Store vial at 4° C prior to opening. Bovine Collagen Type IV is stable at 4° C as an undiluted liquid. Dilute only prior to immediate use. Storing dilutions is not recommended.
Stability Expiration date is six (6) months from date of receipt.
Shipping Blue Ice
Reference Data
RefSeq NP_001290039
Locus ID 1282
Cytogenetics 13q34
Synonyms Type IV collagen, collagen 4, bovine collagen
Summary This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2014
Protein Families for Immunoprecipitation and for Western blotting, Suitable for use as a Control or Standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve
Protein Pathways ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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