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Collagen type I Human Protein

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SKU
RA001
Human Collagen Type I
Size:
500 ug
  $790.00
2 Weeks*
Bulk/Customize

Other products for "Collagen I or NM_000088"

Specifications
Specifications
Product Data
Species Human
Protein Source Placenta
Concentration 1.0 mg/ml by nanodrop at 205 nm
Purity Human Collagen type I has been prepared from human placenta and is chromatographically and immunologically pure. This product is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins.  Human Collagen type I reacts with anti-Collagen Type I.  Reaction of Human Collagen type I with Rockland’s anti-Collagen II, III, IV, V or VI is negligible.
Buffer 0.5 M Acetic Acid
Preparation Liquid (sterile filtered) purified Ig fraction.
Recommended Dilution ELISA,Immunohistochemistry,Western Blot
Protein Description This product has been prepared from Human placenta and is free from other Collagens, Human serum proteins and non-collagen extracellular matrix proteins. It reacts with anti-Collagen Type I. Reaction of Human Collagen type I with anti-Collagen II, III, IV, V or VI is negligible (typically less than 1% cross reactivity was detected by ELISA).
Note Human Collagen type I purified protein standard has been tested in SDS-PAGE and western blot. This product is suitable for ELISA and 2D culture. Collagen type I is recognized by type specific anti-collagen antibodies that recognize a native three-dimensional structure.
Storage Store vial at 4° C prior to opening. This product is stable at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Stability Expiration date is six (6) months from date of receipt.
Shipping Blue Ice
Reference Data
RefSeq NP_000079
Locus ID 1277
Cytogenetics 17q21.33
Synonyms Type I collagen, collagen 1, human collagen
Summary This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. provided by R. Dalgleish, Feb 2008
Protein Categories Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families For use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.
Protein Pathways ECM-receptor interaction, Focal adhesion
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Documents
Resources

file-alt Citations

Monitoring the Remodeling of Biohybrid Tissue-Engineered Vascular Grafts by Multimodal Molecular Imaging
Rama, Mohapatra, Melcher et al
Adv Sci (Weinh) (2022) 9 (10), e2105783 DOI: 10.1002/advs.202105783
Cited by 25
AI Summary: Based on the provided abstract and snippet, there is **no mention of any OriGene products** in the referenced paper, and therefore OriGene products did not contribute to this study.
Snippet: ‐human alpha‐smooth muscle actin (_α_‐SMA) (Sigma‐Aldrich, Darmstadt, Germany);monoclonal, anti‐human CD31 (Sigma‐Aldrich, Darmstadt, Germany);polyclonal, anti‐human type I collagen (Acris Antibodies GmbH, Herford, Germany);polyclonal, anti‐human type IV collagen (Acris Antibodies GmbH, Herford, Germany);polyclonal, anti‐human elastin (Acris Antibodies GmbH, Herford, Germany;- Tissue‐engineered va...
Showing 1-1 of 1 papers.
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