Complement C3b Human Protein

SKU BA150

Complement C3b human protein, 0.1 mg

Product Data

• Species: Human
• Protein Source: Serum
• Concentration: lot specific
• Purity: >90% by SDS-PAGE
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified Antigen; Buffer System: PBS, pH 7.2; Preservative: None; Stabilizer: None
• Preparation: Liquid purified Antigen
• Recommended Dilution: ELISA.
• Protein Description: Purified complemet component 3b (C3b) from Human serum. ; Disease status: Source serum was tested negative for HBsAg and for antibodies to HIV and HCV.
• Storage: Store (aliquotted) at -20°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_000055
• Locus ID: 718
• Cytogenetics: 19p13.3
• Synonyms: CPAMD1, Complement component 3
• Summary: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
• Protein Families: <strong>ELISA.</strong>
• Protein Pathways: Complement and coagulation cascades, Systemic lupus erythematosus