Cathepsin G Human Protein

SKU
BA117
Cathepsin G human protein, 0.1 mg
  $1,065.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Protein Source Neutrophils
Purity >95% pure (SDS-PAGE)
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized purified fraction (>95% by SDS-PAGE) containing no preservatives.
Bioactivity Biological (Lot dependent): 2-4 U/mg protein.
One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-ala-ala-pro-phe-pNA (1mM) per minute at 25°C in 160 mM Tris HCl, pH 7.4 containing 1.6 M NaCl.
Reconstitution Method Reconstitute with 86.2 µL using 50 mM Na Acetate, pH 5.5, with 150 mM Sodium Chloride as the buffer to be added to the salt-free lyophilized solid.
Preparation Lyophilized purified fraction (>95% by SDS-PAGE) containing no preservatives.
Protein Description Human Neutrophil Cathepsin G
Note Caution: All human source materials have tested negative for HIV 1,
HIV 2 and non-reactive for anti-HCV, HBsAg and anti-HBc. No test guarantees a product to be non-infectious. Therefore, all materials derived from human fluids or tissues should be considered as potentially infectious.
Storage Store the antigen upon receipt at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: six months from despatch.
Shipping Ambient
Reference Data
RefSeq NP_001902
Locus ID 1511
Cytogenetics 14q12
Synonyms CTSG, VSP
Summary The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. provided by RefSeq, Sep 2014
Protein Categories Cytokines, Enzyme: Peptidases, Intracellular Proteins
Protein Families Druggable Genome, Protease
Protein Pathways Lysosome, Neuroactive ligand-receptor interaction, Renin-angiotensin system, Systemic lupus erythematosus
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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