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Apolipoprotein H / Apo H Human Protein

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SKU
BA1044
Apolipoprotein H / Apo H human protein, 1 mg
Size:
1 mg
  $1,915.00
2 Weeks*
Bulk/Customize

Other products for "APOH or NM_000042"

Specifications
Specifications
Product Data
Species Human
Protein Source Plasma
Concentration lot specific
Purity >95% >95 % pure (SDS-PAGE).
Presentation State Purified
Buffer Presentation State: Purified
State: Liquid protein purified by column chromatography.
Buffer System: 20 mM HEPES-NaOH, 0.16 M Sodium Chloride, pH 7.5 with 0.1 mM PMSF, 20% glycerol, containing 0.1% bromo-nitro-dioxane/methylisothiazoline as preservative
Preparation Liquid protein purified by column chromatography.
Recommended Dilution ELISA: 0.4-0.8 µg/well.
After thawing, mix thoroughly by vortexing before use!
Protein Description Highy pure Beta 2 Glycoprotein I also known as Apolipoprotein H. Human IgA, IgG and IgM are not detectable by Western blot.
Note Caution: All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
Storage Store the antigen at -20 °C or -70 °C. Avoid multiple freeze/thaw cycles.
Stability Shelf life: six months from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_000033
Locus ID 350
Cytogenetics 17q24.2
Synonyms Beta-2-glycoprotein I, Beta2GPI, B2GPI, ApoH, Apo-H, APC Inhibitor, Anticardiolipin Cofactor, B2G1
Summary Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.provided by RefSeq, Dec 2019
Protein Categories Intracellular Proteins, Secreated Proteins
Protein Families ELISA: 0.4-0.8 µg/well.
After thawing, mix thoroughly by vortexing before use!
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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