Kallikrein-3 / PSA / KLK3 (PSA-ACT Complex) Human Protein

SKU
BA1022
Kallikrein-3 / PSA / KLK3 (PSA-ACT Complex) human protein, 50 µg
  $2,040.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Protein Source Seminal Fluid
Purity >95% purity by SDS Page
Presentation State Purified
Buffer Presentation State: Purified
State: Liquid purified fraction
Buffer System: 10 mM Sodium Acetate, 0.15M Sodium Chloride, pH 5.6, 0.05% (w/v) Sodium Azide
Preparation Liquid purified fraction
Note Caution: Status: Starting material was tested and found negative for antibodies to HIV and HBsAg. How ever, all human derived materila should be treated as potentially infectious.
Storage Store at 2-8°C for up to 3 weeks. For long term storage, aliquot and store at -20°C for up to one year.
Shipping Blue Ice
Reference Data
RefSeq NP_001025218
Locus ID 354
Cytogenetics 19q13.33
Synonyms Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
Summary Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease which is synthesized in the epithelial cells of the prostate gland, and is present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. The serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. provided by RefSeq, Dec 2019
Protein Categories Enzyme: Peptidases, Secreated Proteins
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Pathways in cancer, Prostate cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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