Alpha-1-antitrypsin Human Protein

CAT#: BA045

Alpha-1-antitrypsin human protein, 2 mg

Specifications

Product Data

• Species: Human
• Protein Source: Serum
• Concentration: lot specific
• Purity: >95% >96% (SDS-PAGE) Identity confirmed by radial immunodiffusion, SDS-PAGE (single band at 54 kDa) and Cellulose acetate electrophoresis.
• Buffer: State: Liquid
• Preparation: Liquid
• Applications: ELISA. Can be used for all immunological/laboratory methods requiring highly purified antigens.
• Protein Description: Purified human alpha-1 antitrypsin
• Storage: Store at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.

Reference Data

• RefSeq: NP_000286
• Locus ID: 5265
• Cytogenetics: 14q32.13
• Synonyms: A1A; A1AT; AAT; alpha1AT; nNIF; PI; PI1; PRO2275
• Summary: The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: Complement and coagulation cascades