Alpha-1-antitrypsin Human Protein

SKU BA045

Alpha-1-antitrypsin human protein, 2 mg

Product Data

• Species: Human
• Protein Source: Serum
• Concentration: lot specific
• Purity: >96% (SDS-PAGE) Identity confirmed by radial immunodiffusion, SDS-PAGE (single band at 54 kDa) and Cellulose acetate electrophoresis.
• Buffer: Liquid in PBS without stabilizers or preservatives
• Recommended Dilution: ELISA. Can be used for all immunological/laboratory methods requiring highly purified antigens.
• Protein Description: Purified human alpha-1 antitrypsin
• Storage: Store at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_000286
• Locus ID: 5265
• Cytogenetics: 14q32.13
• Synonyms: SERPINA1, AAT
• Summary: The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]
• Protein Families: ELISA. Can be used for all immunological/laboratory methods requiring highly purified antigens.
• Protein Pathways: Complement and coagulation cascades