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ADAR Mutant (K744R) Human Recombinant Protein

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SKU
TP701139
Purified mutant recombinant protein of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 4, mutation at（K744R)
Size:
20 ug
  $900.00
In Stock*
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Other products for "ADAR1 or NM_001025107"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC219761, encoding the full-length of ADAR(K744R)
Tag Myc-DDK
Predicted MW 103.5 kDa
Concentration >0.05 µg/µL as determined by microplate Bradford method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001020278.1
Locus ID 103
Cytogenetics 1q21.3
RefSeq Size 6532
RefSeq ORF 2793
Synonyms ADAR1; AGS6; DRADA; DSH; DSRAD; G1P1; IFI-4; IFI4; K88DSRBP; P136
Summary This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2010
Protein Categories Immune system diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Cytosolic DNA-sensing pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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