USP8 (NM_001128610) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC226336 |
| Predicted MW | 127.3 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001122082 |
| RefSeq ORF | 3354 |
| Synonyms | HumORF8; PITA4; SPG59; UBPY |
| Locus ID | 9101 |
| UniProt ID | P40818 |
| Cytogenetics | 15q21.2 |
| Summary | This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants. provided by RefSeq, Sep 2013 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Endocytosis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "USP8" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH316926 | USP8 MS Standard C13 and N15-labeled recombinant protein (NP_005145) | 10 ug |
$3,360.00
|
|
| LC417494 | Lyophilized USP8 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426972 | Lyophilized USP8 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY417494 | Transient overexpression lysate of ubiquitin specific peptidase 8 (USP8), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY426972 | Transient overexpression lysate of ubiquitin specific peptidase 8 (USP8), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| TP316926 | Recombinant protein of human ubiquitin specific peptidase 8 (USP8), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
| TP326336 | Purified recombinant protein of Homo sapiens ubiquitin specific peptidase 8 (USP8), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
Citations
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