MVK (NM_001114185) Human Mass Spec Standard

SKU
PH325616
MVK MS Standard C13 and N15-labeled recombinant protein (NP_001107657)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225616
Predicted MW 42.5 kDa
Protein Sequence
Protein Sequence
>RC225616 protein sequence
Red=Cloning site Green=Tags(s)

MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSL
DTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPG
AGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTW
GGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLG
EMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQ
PEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001107657
RefSeq Size 2075
RefSeq ORF 1188
Synonyms LRBP; MK; MVLK; POROK3
Locus ID 4598
UniProt ID Q03426
Cytogenetics 12q24.11
Summary This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Terpenoid backbone biosynthesis
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Resources
Other "MVK" proteins (7)
SKU Description Size Price
PH301971 MVK MS Standard C13 and N15-labeled recombinant protein (NP_000422) 10 ug
$3,360.00
LC424723 Lyophilized MVK HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426476 Lyophilized MVK HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424723 Transient overexpression lysate of mevalonate kinase (MVK), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY426476 Transient overexpression lysate of mevalonate kinase (MVK), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP301971 Recombinant protein of human mevalonate kinase (MVK), transcript variant 1, 20 µg 20 ug
$867.00
TP325616 Recombinant protein of human mevalonate kinase (MVK), transcript variant 2, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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