MVK (NM_001114185) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC225616 |
| Predicted MW | 42.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001107657 |
| RefSeq Size | 2075 |
| RefSeq ORF | 1188 |
| Synonyms | LRBP; MK; MVLK; POROK3 |
| Locus ID | 4598 |
| UniProt ID | Q03426 |
| Cytogenetics | 12q24.11 |
| Summary | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014 |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MVK" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301971 | MVK MS Standard C13 and N15-labeled recombinant protein (NP_000422) | 10 ug |
$3,360.00
|
|
| LC424723 | Lyophilized MVK HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426476 | Lyophilized MVK HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424723 | Transient overexpression lysate of mevalonate kinase (MVK), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426476 | Transient overexpression lysate of mevalonate kinase (MVK), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP301971 | Recombinant protein of human mevalonate kinase (MVK), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
| TP325616 | Recombinant protein of human mevalonate kinase (MVK), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
Citations
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