GAK (NM_005255) Human Mass Spec Standard

CAT#: PH323572

GAK MS Standard C13 and N15-labeled recombinant protein (NP_005246)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description GAK MS Standard C13 and N15-labeled recombinant protein (NP_005246)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223572
Predicted MW 143 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_005246
RefSeq Size 4331
RefSeq ORF 3933
Synonyms DNAJ26; DNAJC26
Locus ID 2580
Cytogenetics 4p16.3
Summary In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Protein Pathways
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