PTP alpha (PTPRA) (NM_002836) Human Mass Spec Standard

SKU
PH322592
PTPRA MS Standard C13 and N15-labeled recombinant protein (NP_002827)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222592
Predicted MW 90.72 kDa
Protein Sequence
Protein Sequence
>RC222592 representing NM_002836
Red=Cloning site Green=Tags(s)

MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNIT
LGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEPWEGNSSTAATTPETFPPSGN
SDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLAR
SPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHS
RVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKC
AQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM
LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQ
YVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMK
KNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIV
MLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEV
GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQ
RPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_002827
RefSeq Size 3643
RefSeq ORF 2406
Synonyms HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RPTPA
Locus ID 5786
UniProt ID P18433
Cytogenetics 20p13
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. provided by RefSeq, Jul 2008
Protein Families Druggable Genome, Phosphatase, Transmembrane
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Other "PTP alpha" proteins (9)
SKU Description Size Price
PH304392 PTPRA MS Standard C13 and N15-labeled recombinant protein (NP_543031) 10 ug
$3,360.00
LC401026 Lyophilized PTPRA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC409009 Lyophilized PTPRA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC409010 Lyophilized PTPRA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401026 Transient overexpression lysate of protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY409009 Transient overexpression lysate of protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY409010 Transient overexpression lysate of protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP304392 Recombinant protein of human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 3, 20 µg 20 ug
$737.00
TP322592 Recombinant protein of human protein tyrosine phosphatase, receptor type, A (PTPRA), transcript variant 1, 20 µg 20 ug
$737.00

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