GIT1 (NM_014030) Human Mass Spec Standard

SKU
PH320153
GIT1 MS Standard C13 and N15-labeled recombinant protein (NP_054749)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220153
Predicted MW 84.2 kDa
Protein Sequence
Protein Sequence
RC220153
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_054749
RefSeq Size 3758
RefSeq ORF 2283
Locus ID 28964
UniProt ID Q9Y2X7
Cytogenetics 17q11.2
Summary GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve ENTR1 and PTPN13 (By similarity).UniProtKB/Swiss-Prot Function
Protein Families Druggable Genome
Protein Pathways Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Regulation of actin cytoskeleton
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Other "GIT1" proteins (3)
SKU Description Size Price
LC415510 Lyophilized GIT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415510 Transient overexpression lysate of G protein-coupled receptor kinase interacting ArfGAP 1 (GIT1), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP320153 Recombinant protein of human G protein-coupled receptor kinase interacting ArfGAP 1 (GIT1), transcript variant 2, 20 µg 20 ug
$867.00

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