HFE (NM_139009) Human Mass Spec Standard

SKU
PH319465
HFE MS Standard C13 and N15-labeled recombinant protein (NP_620578)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219465
Predicted MW 35.1 kDa
Protein Sequence
Protein Sequence
>RC219465 representing NM_139009
Red=Cloning site Green=Tags(s)

MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKG
WDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAW
PTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG
TLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_620578
RefSeq Size 1280
RefSeq ORF 975
Synonyms HFE1; HH; HLA-H; MVCD7; TFQTL2
Locus ID 3077
UniProt ID Q30201
Cytogenetics 6p22.2
Summary The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. provided by RefSeq, Jul 2008
Protein Families Druggable Genome, Transmembrane
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Other "HFE" proteins (11)
SKU Description Size Price
PH317447 HFE MS Standard C13 and N15-labeled recombinant protein (NP_000401) 10 ug
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PH319316 HFE MS Standard C13 and N15-labeled recombinant protein (NP_620575) 10 ug
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LC408433 Lyophilized HFE HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC408436 Lyophilized HFE HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC424725 Lyophilized HFE HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY408433 Transient overexpression lysate of hemochromatosis (HFE), transcript variant 6 (as WB positive control) 100 ug
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LY408436 Transient overexpression lysate of hemochromatosis (HFE), transcript variant 9 (as WB positive control) 100 ug
$436.00
LY424725 Transient overexpression lysate of hemochromatosis (HFE), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP317447 Recombinant protein of human hemochromatosis (HFE), transcript variant 1, 20 µg 20 ug
$867.00
TP319316 Purified recombinant protein of Homo sapiens hemochromatosis (HFE), transcript variant 6, 20 µg 20 ug
$867.00
TP319465 Purified recombinant protein of Homo sapiens hemochromatosis (HFE), transcript variant 9, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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