EDARADD (NM_080738) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC219198 |
| Predicted MW | 23.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_542776 |
| RefSeq Size | 2891 |
| RefSeq ORF | 615 |
| Synonyms | ECTD11A; ECTD11B; ED3; EDA3 |
| Locus ID | 128178 |
| UniProt ID | Q8WWZ3 |
| Cytogenetics | 1q42.3-q43 |
| Summary | This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008 |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "EDARADD" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC403313 | Lyophilized EDARADD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC403442 | Lyophilized EDARADD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403313 | Transient overexpression lysate of EDAR-associated death domain (EDARADD), transcript variant B (as WB positive control) | 100 ug |
$436.00
|
|
| LY403442 | Transient overexpression lysate of EDAR-associated death domain (EDARADD), transcript variant A (as WB positive control) | 100 ug |
$436.00
|
|
| TP319198 | Recombinant protein of human EDAR-associated death domain (EDARADD), transcript variant B, 20 µg | 20 ug |
$867.00
|
|
Citations
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