NR2C2 (NM_003298) Human Mass Spec Standard

CAT#: PH319184

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NR2C2 MS Standard C13 and N15-labeled recombinant protein (NP_003289)



  View other "NR2C2" proteins (3)

USD 3,255.00


Availability*
3 Weeks

Size
    • 10 ug


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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219184
Predicted MW 67.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_003289
RefSeq Size 2416
RefSeq ORF 1845
Synonyms TAK1; TR4
Locus ID 7182
UniProt ID P49116, F2YGU2
Cytogenetics 3p25.1
Summary This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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