TPM1 (NM_001018020) Human Mass Spec Standard

SKU
PH318995
TPM1 MS Standard C13 and N15-labeled recombinant protein (NP_001018020)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218995
Predicted MW 32.6 kDa
Protein Sequence
Protein Sequence
>RC218995 representing NM_001018020
Red=Cloning site Green=Tags(s)

MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDS
LLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK
MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAA
EDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE
LNNM

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001018020
RefSeq Size 1797
RefSeq ORF 852
Synonyms C15orf13; CMD1Y; CMH3; HEL-S-265; HTM-alpha; LVNC9; TMSA
Locus ID 7168
UniProt ID P09493
Cytogenetics 15q22.2
Summary This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. provided by RefSeq, Jul 2008
Protein Families Druggable Genome
Protein Pathways Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
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Other "TPM1" proteins (23)
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PH301262 TPM1 MS Standard C13 and N15-labeled recombinant protein (NP_000357) 10 ug
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PH319652 TPM1 MS Standard C13 and N15-labeled recombinant protein (NP_001018007) 10 ug
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LC422687 Lyophilized TPM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC422688 Lyophilized TPM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC422689 Lyophilized TPM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422690 Lyophilized TPM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422696 Lyophilized TPM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC424765 Lyophilized TPM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY422687 Transient overexpression lysate of tropomyosin 1 (alpha) (TPM1), transcript variant 3 (as WB positive control) 100 ug
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LY422688 Transient overexpression lysate of tropomyosin 1 (alpha) (TPM1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY422689 Transient overexpression lysate of tropomyosin 1 (alpha) (TPM1), transcript variant 4 (as WB positive control) 100 ug
$436.00
LY422690 Transient overexpression lysate of tropomyosin 1 (alpha) (TPM1), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY422696 Transient overexpression lysate of tropomyosin 1 (alpha) (TPM1), transcript variant 7 (as WB positive control) 100 ug
$436.00
LY424765 Transient overexpression lysate of tropomyosin 1 (alpha) (TPM1), transcript variant 5 (as WB positive control) 100 ug
$436.00
TP301262 Recombinant protein of human tropomyosin 1 (alpha) (TPM1), transcript variant 5, 20 µg 20 ug
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TP318007 Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 1, 20 µg 20 ug
$737.00
TP318995 Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 7, 20 µg 20 ug
$737.00
TP319543 Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 3, 20 µg 20 ug
$737.00
TP319606 Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 4, 20 µg 20 ug
$737.00
TP319652 Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 2, 20 µg 20 ug
$737.00

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